Drug Class: What is Celecoxib and why is it prescribed?
Drug Mechanism: How does Celecoxib work?
Dosage; How should you take Celecoxib?
Possible food and drug interactions when taking Celecoxib
Special information on Celecoxib
Celecoxib side effects
|Drug Class: What is Celecoxib and why is it prescribed?|
|Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that relieves pain and inflammation (swelling). Celecoxib is used most commonly used for acute pain, menstrual cramps, and the pain and inflammation of osteoarthritis and rheumatoid arthritis.|
|Drug Mechanism: How does Celecoxib work?|
|Like older NSAIDs such as Motrin and Naprosyn, Celecoxib is believed to
fight pain and inflammation by inhibiting the effect of a natural enzyme called
COX-2. Unlike the older medications, however, Celecoxib does not interfere with a similar
substance, called COX-1, which exerts a protective effect on the lining of the stomach. Celecoxib is therefore less likely to cause the bleeding and ulcers that sometimes accompany sustained use of the older NSAIDs.
Celecoxib has also been found to reduce the number of colorectal polyps(growths in the wall of the lower intestine and rectum) in people who suffer from the condition called familial adenomatous polyposis (FAP), an inherited tendency to develop large numbers of colorectal polyps that eventually become cancerous.
Celecoxib works by blocking the enzyme in your body that makes prostaglandins. Decreasing prostaglandins helps to reduce pain and swelling.
|Dosage; How should you take Celecoxib?|
For best results, take Celecoxib dosage regularly, exactly
as prescribed. You can take Celecoxib with or without food.
Celecoxib dosage is typically cut in half for people with moderate
|Possible food and drug interactions when taking Celecoxib|
If Celecoxib is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Celecoxib with the following:
|Special information on Celecoxib|
|If you are pregnant or breastfeeding, Celecoxib can harm a developing baby,
if taken during the third trimester, and its safety earlier in pregnancy has not
been confirmed. Take Celecoxib during pregnancy only if you feel the risk
It is possible that Celecoxib makes its way into breast milk (scientists are not sure), and it could cause serious reactions in a nursing infant. If Celecoxib is essential to your health, your doctor may advise you to discontinue breastfeeding.
|Celecoxib side effects|
|Celecoxib side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Celecoxib.
More common Celecoxib side effects: May include abdominal pain, diarrhea, headache, indigestion, nausea, respiratory infection, sinus inflammation.
Less common Celecoxib side effects: Back pain, dizziness, gas, insomnia, rash, runny nose, sore throat, swelling.
Rare Celecoxib side effects: May include, allergic reactions, anxiety, belching, blisters in mouth and eyes, blood disorders, blood infections, blurred vision, bone disorders, breast pain, breast problems, bronchitis, cataracts, chest pain, colitis, conjunctivitis (pinkeye), constipation, coughing, cysts, dark-tarry stools, deafness, depression, dermatitis, diabetes, difficult urination, difficulty breathing, difficulty swallowing, drowsiness, dry mouth, dry skin, earache, ear infection, ear ringing, esophageal perforation, eye infection, eye pain, fainting, fatigue, fever, flu symptoms, fungal infection, gallstones, gangrene, general swelling, glaucoma (pressure in the eye), hair loss, heart failure, heart irregularities, hemorrhoids, hepatitis, hernia of the stomach, herpes infection, hives, hot flashes, increased appetite, increased blood pressure, increased heart rate, increased muscle tone, increased urination, infection, inflammation of the digestive tract, inflammation of the bladder, inflammation of the blood vessels, intestinal bleeding, intestinal obstruction or perforation, itching, jaundice, joint pain or inflammation, kidney problems, laryngitis, leg cramps, liver problems, loss of appetite, loss of balance, low blood sugar, menstrual disorders, migraine headache, mouth ulcers, muscle ache, nail disorders, neck stiffness, nerve pain, nervousness, nosebleeds, pain, painful urination, pancreatitis, phlebitis, pneumonia, poor coordination, prostate problems, severe diarrhea, severe skin rash and peeling, skin reaction due to sunlight, skin sensitivity, skin tingling, stroke, suicide, sweating, swollen face and throat, taste disturbances, tendonitis, tiredness, tooth disorders, urinary incontinence, urinary tract infections, vaginal problems, vomiting, weakness, weight gain.
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