Drug Class: What is Zantac ? and why is it prescribed?
Zantac Mechanism: How does Zantac work?
Zantac Dosage: How should you take Zantac
Possible food and drug interactions when taking Zantac
Special information on Zantac
Zantac side effects
|Drug Class: What is Zantac ? and why is it prescribed?|
|Zantac (Ranitidine) is a type of antihistamine that blocks the release of stomach acid.
Zantac is prescribed for the short-term treatment (4 to 8 weeks) of active duodenal ulcer and active benign gastric ulcer, and as maintenance therapy for gastric or duodenal ulcer, at a reduced dosage, after the ulcer has healed. Zantac is also used for the treatment of conditions in which the stomach produces too much acid, such as Zollinger-Ellison syndrome and systemic mastocytosis, for gastroesophageal reflux disease (backflow of acid stomach contents) and for healing of erosive esophagitis (severe inflammation of the esophagus).
Some doctors prescribe Zantac to prevent damage to the stomach and duodenum from long-term use of nonsteroidal anti-inflammatory drugs such as Indocin and Motrin, and to treat bleeding of the stomach and intestine.
Zantac is also sometimes prescribed for stress-induced ulcers.
|Zantac Mechanism: How does Zantac work?|
|Zantac is one of a group of medicines known as H2-receptor antagonists. Zantac acts by blocking histamine receptors, which are present on the cells in the stomach lining.
Normally a substance called histamine binds to these receptors. Histamine is a chemical produced throughout the body and has many effects. When histamine binds to H2 receptors on cells in the stomach lining, it causes them to produce acid.
Zantac binds to H2 receptors, replacing some of the histamine. As a result, the amount of stomach acid produced by these cells is decreased.
Stomach acid is present as a normal part of the digestive process. If large amounts of stomach acid are produced this can cause the pain in the abdomen commonly known as indigestion. The excess acid may also flow back into the food pipe (oesophagus) causing pain and a burning sensation known as heartburn.
Normally the lining of the stomach and duodenum (an area of the intestine directly after the stomach) has a protective layer, which resists acid attack. If this layer is damaged, or large amounts of stomach acid are formed, a peptic ulcer can develop.
Zantac decreases the amount of acid in the stomach and duodenum. As a result, Zantac helps relieve the symptoms of indigestion and aids the healing of ulcers. Zantac is also used to depress acid production in various other conditions.
|Zantac Dosage: How should you take Zantac|
|Take Zantac exactly as prescribed by your doctor. Make sure you follow the diet your doctor recommends.
You can take an antacid for pain while you are taking Zantac.
Other Excess Acid Conditions (such as Zollinger-Ellison Syndrome)
Benign Gastric Ulcer and Gastroesophageal Reflux Disease (GERD)
Gastroesophageal Reflux Disease (GERD) and Erosive Esophagitis
If you miss a Zantac dose
Symptoms of Zantac overdose may include
Zantac Storage instructions
Zantac Preparations: Tablet- 150mg, 300mg
|Possible food and drug interactions when taking Zantac|
The following drugs may interact with Zantac
Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way Zantac works. Check with your health care professional before stopping or starting any of your medicines.
|Special information on Zantac|
|Most Important Fact about Zantac
Zantac helps to prevent the recurrence of gastric or duodenal ulcers and aids the healing of ulcers that do occur.
Zantac precautions if you are pregnant or breastfeeding
Zantac may pass into breast milk. Zantac should not be used during breastfeeding unless considered essential by your doctor. Seek medical advice from your doctor.
Special warnings about Zantac
Do not smoke cigarettes or drink alcohol; these increase irritation in your stomach and can lengthen the time it will take for ulcers to heal. Cigarettes and alcohol can also worsen acid reflux or heartburn.
If you need to take an antacid you should take it at least 1 hour before or 1 hour after Zantac. Zantac will not be as effective if taken at the same time as an antacid.
If you get black, tarry stools or vomit up what looks like coffee grounds, call your prescriber or health care professional at once. You may have a bleeding ulcer.
|Zantac side effects|
|Zantac should not be used if you suffer from life long inherited blood disease characterized by sudden attacks of high blood pressure, mental disturbances and abdominal pain (acute intermittent porphyria).
Zantac should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using Zantac and inform your doctor or pharmacist immediately.
Possible Zantac Side effects
Less common side effects of Zantac may include:
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