Drug Class: What is alfuzosin and why is it prescribed?
Drug Mechanism: How does alfuzosin work?
Dosage: How should you take alfuzosin?
Possible food and drug interactions when taking alfuzosin
Special information on alfuzosin
Alfuzosin side effects
|Drug Class: What is alfuzosin and why is it prescribed?|
|Alfuzosin is in a group of drugs called alpha-adrenergic blockers. Alfuzosin relaxes the muscles in the prostate and bladder neck, making it easier to urinate. Alfuzosin is used to improve urination in men with benign prostatic hyperplasia (enlarged prostate).|
|Drug Mechanism: How does alfuzosin work?|
|Alfuzosin is a selective alpha-1 adrenoceptor antagonist, with structural similarities to prazosin. In vitro and in vivo studies have demonstrated potent and selective alpha-1 adrenoceptor antagonistic effects of alfuzosin on the genitourinary tract (proximal urethral, bladder base, prostatic and prostatic capsule smooth muscle. Studies suggest that alfuzosin is more selective for alpha-1 receptors in the genitourinary tract compared to the vasculature than prazosin or terazosin and may reduce urethral resistance at doses not affecting blood pressure.|
|Dosage: How should you take alfuzosin?|
|Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Alfuzosin is usually taken once a day, just after a meal. Try to take this medication at the same time each day. Do not take it on an empty stomach. Do not crush, chew, or break an extended-release tablet. Swallow it whole. Breaking the pill may cause too much of the drug to be released at one time. Alfuzosin lowers blood pressure and may cause dizziness or fainting, especially when you first start taking it, or when you start taking|
|Possible food and drug interactions when taking alfuzosin|
|you should not use alfuzosin if you are allergic to it, if you have severe liver disease, or if you are also using ketoconazole (Nizoral), itraconazole (Sporanox), or ritonavir (Norvir). Do not take alfuzosin with other similar medicines such as doxazosin (Cardura), prazosin (Minipress), silodosin (Rapaflo), tamsulosin (Flomax), or terazosin (Hytrin). Alfuzosin may cause dizziness or fainting. Be careful if you drive or do anything that requires you to be alert. Avoid standing for long periods of time or becoming overheated during exercise and in hot weather. Avoid getting up too fast from a sitting|
|Special information on alfuzosin|
|Alfuzosin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. To prevent dizziness, avoid standing for long periods of time or becoming overheated during exercise and in hot weather. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. Drinking alcohol can increase certain side effects of alfuzosin. What happens if I miss a dose? Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do|
|Alfuzosin side effects|
| Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using alfuzosin and call your doctor at once if you have a serious side effect such as:
new or worsening chest pain;
Less serious side effects
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